Biological Target
ABL proto-oncogene 1, non-receptor tyrosine kinase
Biological Target
ABL proto-oncogene 1, non-receptor tyrosine kinase Description
ABL proto-oncogene 1 is a ubiquitous cytoplasmic and nuclear non-receptor tyrosine kinase that plays critical roles in cell proliferation, differentiation, adhesion, and apoptosis. It acts as a signaling molecule by phosphorylating various intracellular substrates, modulating their activity or localization. ABL1 is involved in various cellular processes including cytoskeletal dynamics, DNA damage response, and cell cycle progression.
Medications Targeting ABL proto-oncogene 1, non-receptor tyrosine kinase
No approved therapeutics or investigational compounds are currently cataloged for this target in our database.