Pharmacological Drug Classes

Explore therapeutic drug families grouped by biochemical mechanism of action, cellular receptors, and physiological organ systems.

75 classes available
Drug Class
Endocrine System Adrenal Glands

Adrenal cortical steroids

Target: Glucocorticoid receptor and mineralocorticoid receptor

Adrenal cortical steroids, also known as corticosteroids, are natural hormones produced by the adrenal glands that help the body manage stress, inflammation,…

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Drug Class
Endocrine System Reproductive Organs

Sex hormone combinations

Target: Estrogen receptor and Progesterone receptor

Sex hormone combinations are medications that contain two types of sex hormones, such as estrogen with progestin or estrogen with androgen. These…

11 medications linked Explore Class →
Drug Class
Endocrine System Reproductive Organs

Sex hormones

Target: Estrogen receptor, Progesterone receptor, Androgen receptor

Sex hormones are natural chemicals in the body that control sexual development and reproduction. They include estrogens and progestins (female hormones) and…

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Drug Class
Endocrine System Kidneys

SGLT-2 inhibitors

Target: SGLT-2 protein

SGLT-2 inhibitors are a class of medications used to lower high blood sugar levels in people with type 2 diabetes. They are…

6 medications linked Explore Class →
Drug Class
Nervous System Skeletal Muscle

Skeletal muscle relaxant combinations

Target: Central nervous system receptors (e.g., GABA receptors, NMDA receptors)

Skeletal muscle relaxant combinations are medications that combine a muscle relaxant with other drugs, such as pain relievers, in a single pill.…

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Drug Class
Nervous System Skeletal Muscles

Skeletal muscle relaxants

Target: GABA-B receptor (for baclofen), alpha-2 adrenergic receptor (for tizanidine), ryanodine receptor (for dantrolene), SNAP-25 (for botulinum toxins)

Skeletal muscle relaxants are medications that help reduce muscle tension and spasms. They are often called muscle relaxants and can work in…

16 medications linked Explore Class →
Drug Class
Nervous System Brain

Smoking cessation agents

Target: Nicotinic acetylcholine receptor

Smoking cessation agents are medicines that help people quit smoking by reducing cravings and withdrawal symptoms.

3 medications linked Explore Class →
Drug Class
Endocrine System Hypothalamus, Pancreas, Gastrointestinal Tract

Somatostatin and somatostatin analogs

Target: Somatostatin receptors (SSTR1-5)

Somatostatin and somatostatin analogs are medications that mimic a natural hormone in the body. This hormone helps regulate the release of other…

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Drug Class
Reproductive System Sperm cells

Spermicides

Target: Sperm cell membrane

Spermicides are chemicals that kill sperm to prevent pregnancy. They come in forms like creams, jellies, and foams.

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Drug Class
Cardiovascular System Liver

Statins

Target: HMG-CoA reductase

Statins are a class of medications that lower cholesterol levels in the blood. They are often prescribed to reduce the risk of…

8 medications linked Explore Class →
Drug Class
Urinary System Bladder

Sterile irrigating solutions

Target: Water

Sterile irrigating solutions are sterile, nonpyrogenic isotonic solutions used for washing, irrigation, and rinsing of body cavities, wounds, and surgical sites.

4 medications linked Explore Class →
Drug Class
Infectious Disease / Immune System Bacterial Ribosome

Streptogramins

Target: 50S ribosomal subunit

Streptogramins are a type of antibiotic used to treat serious bacterial infections. They are made from two different components that work together…

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Drug Class
Respiratory System Lungs

Streptomyces derivatives

Target: 30S ribosomal subunit

Streptomyces derivatives are a class of antibiotics that fight certain bacterial infections, including tuberculosis. They are used when other treatments have not…

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Drug Class
Nervous System Thalamus

Succinimide anticonvulsants

Target: T-type calcium channel

Succinimide anticonvulsants are a class of medications primarily used to control absence seizures, a type of epilepsy characterized by brief staring spells.

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Drug Class
Multiple systems (primarily Urinary System for antibiotics, but also Endocrine, Cardiovascular, etc.) Kidneys

Sulfonamides

Target: Dihydropteroate synthetase (for antibiotics)

Sulfonamides, also known as sulfa drugs, are a group of synthetic medicines that include antibiotics and non-antibiotic drugs used for conditions like…

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Drug Class
Endocrine System Pancreas

Sulfonylureas

Target: ATP-sensitive potassium channel

Sulfonylureas are a class of medications used to manage type 2 diabetes by helping the pancreas release more insulin.

3 medications linked Explore Class →
Drug Class
Endocrine System Ovaries

Synthetic ovulation stimulants

Target: Estrogen receptor

Synthetic ovulation stimulants are medications that help women who have trouble ovulating (releasing an egg) to become fertile. They work by tricking…

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Drug Class
Nervous System Brain

Tetracyclic antidepressants

Target: Serotonin and noradrenaline reuptake transporters

Tetracyclic antidepressants are a class of medications used to treat depression. They have a unique chemical structure with four rings and work…

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Drug Class
Nervous System Brain

Tetracyclines

Target: GABA-A receptor

Benzodiazepines are a class of medications that act as central nervous system depressants. They are commonly used to treat anxiety, insomnia, seizures,…

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Drug Class
Endocrine System Cancerous tissue

Therapeutic radiopharmaceuticals

Target: DNA in cancer cells

Therapeutic radiopharmaceuticals are radioactive drugs used in higher doses to treat certain cancers and other diseases by delivering radiation directly to the…

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Drug Class
Immune System Immune System

Therapeutic vaccines

Target: Antigens (cancer-specific or pathogen-specific)

Therapeutic vaccines are a type of treatment that uses the body's own immune system to fight diseases, such as cancer or infections.…

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Drug Class
Urinary System Kidneys

Thiazide diuretics

Target: Sodium/chloride cotransporter (NCC) in the distal convoluted tubule

Thiazide diuretics are a type of medication that helps your body get rid of extra fluid by increasing urine production. They are…

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Drug Class
Endocrine System Adipose Tissue

Thiazolidinediones

Target: Peroxisome proliferator-activated receptor-gamma (PPARγ)

Thiazolidinediones, also known as glitazones, are a class of oral medications used to treat type 2 diabetes. They help lower blood sugar…

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Drug Class
Nervous System Brain

Thioxanthenes

Target: Dopamine-2 (D2) receptor

Thioxanthenes are a class of typical antipsychotic medications used to manage mental health conditions like schizophrenia. They are related to another group…

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Drug Class
Infectious Disease / Immune System Bacterial Cell Wall

Third generation cephalosporins

Target: Penicillin-binding proteins (PBPs)

Third generation cephalosporins are a group of broad-spectrum antibiotics that kill a wide range of bacteria. They are derived from a mold…

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Drug Class
Cardiovascular System Blood

Thrombin inhibitors

Target: Thrombin

Thrombin inhibitors are a type of medication that helps prevent blood clots from forming. They are often called blood thinners, but they…

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Drug Class
Cardiovascular System Blood vessels

Thrombolytics

Target: Plasminogen

Thrombolytics are emergency medications used to dissolve dangerous blood clots that cause strokes, heart attacks, or pulmonary embolisms.

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Drug Class
Endocrine System Thyroid Gland

Thyroid drugs

Target: Thyroid hormone receptor

Thyroid drugs are medications used to replace or supplement thyroid hormones in people whose thyroid gland does not produce enough. They are…

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Drug Class
Immune System Joints, Skin, Intestines

TNF alfa inhibitors

Target: Tumor Necrosis Factor-alpha (TNF-α)

TNF-alpha inhibitors are a class of medications that block a protein called tumor necrosis factor-alpha (TNF-α), which is involved in causing inflammation…

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Drug Class
Reproductive System Uterus

Tocolytic agents

Target: Beta2-adrenergic receptor

Tocolytic agents, also called labor suppressants, are medications used to delay preterm labor for a short time (usually 48 hours) to allow…

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Drug Class
Integumentary System Skin

Topical acne agents

Target: Retinoic acid receptor

Topical acne agents are creams, gels, lotions, and washes applied to the skin to treat acne. They are often used for mild…

19 medications linked Explore Class →
Drug Class
Integumentary System Skin

Topical agents

Target: Various local targets

Topical agents are medications applied directly to the skin or mucous membranes, such as creams, ointments, lotions, or eye drops, to treat…

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Drug Class
Nervous System Skin

Topical anesthetics

Target: Voltage-gated sodium channels

Topical anesthetics are medications applied directly to the skin or mucous membranes to temporarily numb the area and relieve pain. They come…

19 medications linked Explore Class →
Drug Class
Integumentary System Skin

Topical anti-infectives

Target: Microbial cell wall or membrane components

Topical anti-infectives are medications applied directly to the skin, nails, or mucous membranes to treat infections caused by bacteria, fungi, or viruses.…

20 medications linked Explore Class →
Drug Class
Integumentary System Skin

Topical anti-rosacea agents

Target: Alpha-adrenergic receptor (for vasoconstrictors); various microbial targets (for antibacterial/antiprotozoal agents)

Topical anti-rosacea agents are medications applied to the skin to treat rosacea, a condition causing redness, bumps, and pimples on the face.

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Drug Class
Integumentary System Skin

Topical antibiotics

Target: Bacterial cell wall synthesis enzymes

Topical antibiotics are medications in cream or ointment form that are applied directly to the skin to treat or prevent bacterial infections.

16 medications linked Explore Class →
Drug Class
Integumentary System Skin, nails, hair, mucous membranes

Topical antifungals

Target: Ergosterol synthesis enzymes (e.g., lanosterol 14α-demethylase, squalene epoxidase)

Topical antifungals are medications applied directly to the skin, nails, hair, mouth, or vagina to treat fungal infections. They come in various…

20 medications linked Explore Class →
Drug Class
Immune System Skin, Nose, Eyes

Topical antihistamines

Target: Histamine-1 receptor

Topical antihistamines are medications applied directly to the skin, nose, or eyes to relieve allergy symptoms like itching, swelling, and redness.

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Drug Class
Integumentary System Skin

Topical antineoplastics

Target: Toll-like receptor 7 (TLR7) for imiquimod; thymidylate synthase for fluorouracil; protein kinase C for ingenol; tubulin for tirbanibulin; DNA for mechlorethamine

Topical antineoplastics are medications applied directly to the skin to treat certain types of skin cancer. They work by targeting and destroying…

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Drug Class
Integumentary System Skin

Topical antipsoriatics

Target: Vitamin D receptor, Retinoic acid receptor, Phosphodiesterase-4, Aryl hydrocarbon receptor

Topical antipsoriatics are medications applied directly to the skin to treat psoriasis, a chronic condition causing itchy, dry, scaly patches. They come…

10 medications linked Explore Class →
Drug Class
Integumentary System Skin

Topical antivirals

Target: Viral DNA polymerase

Topical antivirals are creams or ointments applied directly to the skin to treat viral infections like cold sores.

2 medications linked Explore Class →
Drug Class
Integumentary System Skin

Topical astringents

Target: Surface proteins on skin cells

Topical astringents are products applied to the skin that cause tissues to tighten and dry. They help protect minor wounds and soothe…

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Drug Class
Integumentary System Skin

Topical debriding agents

Target: Collagenase

Topical debriding agents are medications applied directly to wounds to help clean them by removing dead tissue and debris, promoting faster healing…

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Drug Class
Integumentary System Skin

Topical depigmenting agents

Target: Tyrosinase enzyme

Topical depigmenting agents are creams or lotions applied to the skin to lighten dark spots or patches caused by excess pigment.

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Drug Class
Integumentary System Skin

Topical emollients

Target: Stratum corneum lipids and proteins

Topical emollients are creams, lotions, or ointments that soothe and soften the skin. They are also called moisturizers and help keep the…

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Drug Class
Integumentary System Skin

Topical keratolytics

Target: Keratin

Topical keratolytics are medications applied to the skin to soften and remove the outer layer of dead skin cells. They help exfoliate…

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Drug Class
Musculoskeletal System Skin

Topical non-steroidal anti-inflammatories

Target: Cyclooxygenase (COX) enzymes

Topical non-steroidal anti-inflammatory drugs (NSAIDs) are creams, gels, or sprays applied directly to the skin over painful joints or bones. They help…

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Drug Class
Integumentary System Skin

Topical photochemotherapeutics

Target: Protoporphyrin IX

Topical photochemotherapeutics are medications applied to the skin that make it more sensitive to light. They are used together with light therapy…

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Drug Class
Integumentary System Skin

Topical rubefacient

Target: TRPV1 receptor

Topical rubefacients are medications applied to the skin that cause redness and a feeling of warmth. They are used to relieve pain…

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Drug Class
Endocrine System Skin

Topical steroids

Target: Glucocorticoid receptor

Topical steroids are medications applied directly to the skin to reduce inflammation, redness, and swelling. They come in various forms like creams,…

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Drug Class
Integumentary System Skin

Topical steroids with anti-infectives

Target: Glucocorticoid receptor

Topical steroids with anti-infectives are combination medications applied to the skin or scalp. They contain a corticosteroid to reduce inflammation and an…

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Drug Class
Cardiovascular System Heart

Transthyretin stabilizers

Target: Transthyretin (TTR) protein

Transthyretin stabilizers are a class of medications that help prevent the breakdown of a specific protein called transthyretin (TTR). This protein normally…

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Drug Class
Nervous System Brain

Triazine anticonvulsants

Target: Presynaptic sodium channels

Triazine anticonvulsants are a class of medications used to control certain types of seizures by stabilizing electrical activity in the brain.

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Drug Class
Nervous System Brain

Tricyclic antidepressants

Target: Norepinephrine and serotonin transporters

Tricyclic antidepressants (TCAs) are a group of medicines used mainly to treat depression, but also other conditions like anxiety, chronic pain, and…

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Drug Class
Cardiovascular System Blood vessels

Ultrasound contrast media

Target: Microbubbles (gas-filled or site-targeted)

Ultrasound contrast media are substances used during an ultrasound to make the images clearer and more detailed. They help doctors see blood…

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Drug Class
Respiratory System Upper Respiratory Tract

Upper respiratory combinations

Target: Histamine H1 receptor, Opioid receptors, Alpha-adrenergic receptors

Upper respiratory combinations are multi-ingredient products designed to relieve symptoms of colds, allergies, or flu, such as cough, congestion, sneezing, and runny…

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Drug Class
Nervous System Brain

Urea anticonvulsants

Target: Voltage-gated sodium channels

Urea anticonvulsants are a class of medications that were designed to treat seizures with fewer birth defects and liver problems than older…

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Drug Class
Urinary System Liver

Urea cycle disorder agents

Target: Urea cycle enzymes

Urea cycle disorder agents are medications used to treat rare genetic conditions that prevent the body from properly removing ammonia, a toxic…

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Drug Class
Urinary System Bladder

Urinary anti-infectives

Target: Bacterial enzymes (e.g., bacterial nitroreductase for nitrofurantoin)

Urinary anti-infectives are medications used to prevent or treat infections in the urinary tract, such as the bladder and urethra.

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Drug Class
Nervous System Bladder

Urinary antispasmodics

Target: M3 muscarinic receptor

Urinary antispasmodics are a class of medications that help relax the bladder muscle, reducing sudden urges to urinate and controlling bladder spasms.

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Drug Class
Urinary System Kidneys

Urinary pH modifiers

Target: Hydrogen ions

Urinary pH modifiers are medications that change the acidity of your urine, making it less acidic (more alkaline). They are used to…

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Drug Class
Reproductive System Uterus

Uterotonic agents

Target: Oxytocin receptor

Uterotonic agents are medications that make the uterus contract more strongly and frequently. They are used to start or strengthen labor, manage…

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Drug Class
Immune System Immune System

Vaccine combinations

Target: Antigens

Vaccine combinations are single shots that protect against multiple diseases or multiple strains of the same disease. They combine different vaccines into…

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Drug Class
Reproductive System Vagina

Vaginal anti-infectives

Target: Fungal cell membrane ergosterol (for antifungals) / Bacterial ribosome (for antibacterials)

Vaginal anti-infectives are medications used to treat infections in the vagina. They come in forms like creams, tablets, gels, or solutions that…

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Drug Class
Reproductive System Vagina

Vaginal preparations

Target: Estrogen receptor

Vaginal preparations are medications that are inserted or applied directly into the vagina to treat various vaginal conditions. They come in forms…

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Drug Class
Cardiovascular System Blood Vessels

Vasodilators

Target: Guanylate cyclase

Vasodilators are medications that widen blood vessels, making it easier for blood to flow through them. They are used to treat conditions…

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Drug Class
Endocrine System Kidneys

Vasopressin antagonists

Target: Vasopressin receptors (V1A, V1B, V2)

Vasopressin antagonists are a class of medications that block the effects of vasopressin, a hormone that helps regulate water balance and blood…

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Drug Class
Cardiovascular System Blood Vessels

Vasopressors

Target: Alpha-1 adrenergic receptor

Vasopressors are medications that help raise blood pressure by tightening blood vessels. They are often used in emergency situations when blood pressure…

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Drug Class
Cardiovascular System Blood Vessels

VEGF/VEGFR inhibitors

Target: Vascular Endothelial Growth Factor Receptor (VEGFR)

VEGF/VEGFR inhibitors are medications that block the activity of vascular endothelial growth factor (VEGF) and its receptor (VEGFR), which are proteins that…

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Drug Class
Immune System Immune System

Viral vaccines

Target: Viral antigens

Viral vaccines are medications that help your body build protection against specific viruses. They contain either killed (inactivated) viruses or weakened (live…

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Drug Class
Musculoskeletal System Knee Joint

Viscosupplementation agents

Target: Hyaluronic acid

Viscosupplementation agents are treatments that contain hyaluronic acid, a natural substance injected into the knee joint to relieve pain from osteoarthritis.

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Drug Class
Musculoskeletal System Knee Joint

Viscosupplementation agents

Target: Hyaluronic acid

Viscosupplementation agents are treatments that contain hyaluronic acid, a natural substance injected into the knee joint to relieve pain from osteoarthritis.

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Drug Class
Endocrine System Whole Body

Vitamin and mineral combinations

Target: Various vitamins and minerals

Vitamin and mineral combinations are supplements that provide essential nutrients your body needs in small amounts for proper growth, development, and overall…

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Drug Class
Endocrine System Various organs

Vitamins

Target: Various vitamins (e.g., vitamin D receptor, cofactors for enzymes)

Vitamins are essential nutrients that your body needs in small amounts to stay healthy. They are found naturally in foods, but your…

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Drug Class
Nervous System Brain

VMAT2 inhibitors

Target: VMAT2 (vesicular monoamine transporter-2)

VMAT2 inhibitors are a class of medications used to reduce involuntary movements in conditions like Huntington's disease and tardive dyskinesia.

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