Medication
Drug Class: Angiotensin Receptor-Neprilysin Inhibitor (ARNI)
Small molecule
Mechanism of Action of Sacubitril / Valsartan
INN: Sacubitril / Valsartan · Pharmacological Reference Profile
- Biological Target Angiotensin II receptor type 1 (AT1) and Neprilysin
- Drug Class Angiotensin Receptor-Neprilysin Inhibitor (ARNI)
- Physiological System Cardiovascular System
- Molecular Modality Small molecule
How Sacubitril / Valsartan Works
BIOCHEMICAL TARGET PATHWAY
Sacubitril / Valsartan → [ Angiotensin II receptor type 1 (AT1) and Neprilysin ] → Clinical Effector Response
Detailed pharmacological mechanism under curation.
REGISTERED FORMULATIONS
Commercial Brands (1)
Entresto