Serotonin Transporter
Biological Target
Serotonin Transporter Description
The Serotonin Transporter (SERT) is an integral membrane protein primarily located on the presynaptic terminals of serotonergic neurons. Its essential physiological function is to reuptake serotonin (5-HT) from the synaptic cleft back into the presynaptic neuron. This reuptake process is crucial for regulating the extracellular concentration and duration of serotonin signaling, thereby profoundly impacting mood, emotion, sleep, and pain perception.
Medications Targeting Serotonin Transporter
No approved therapeutics or investigational compounds are currently cataloged for this target in our database.