P2Y purinoceptor 12
Biological Target
P2Y purinoceptor 12 Description
P2Y12 is a G protein-coupled receptor primarily expressed on the surface of platelets. This receptor binds adenosine diphosphate (ADP), a potent activator of platelets released from damaged cells and activated platelets themselves. Upon ADP binding, P2Y12 activation initiates a signaling cascade that is crucial for platelet shape change, granule secretion, and aggregation, ultimately contributing to thrombus formation and hemostasis.
Medications Targeting P2Y purinoceptor 12
No approved therapeutics or investigational compounds are currently cataloged for this target in our database.