VMAT2 inhibitors

System Nervous System

Organ Brain

Target Type Pump

Biological Target VMAT2 (vesicular monoamine transporter-2)

Class Overview

VMAT2 inhibitors are a class of medications used to reduce involuntary movements in conditions like Huntington's disease and tardive dyskinesia.

Mechanism of Action

They work by blocking a protein called VMAT2 in the brain, which reduces the amount of chemical messengers (neurotransmitters) released between nerve cells, thereby decreasing uncontrolled movements.

Active Substances in this Class (14)

Acetaminophen Apixaban Aspirin Bupropion Clonidine Dextroamphetamine / Amphetamine Digoxin Heparin Ketamine Metformin Methotrexate Octreotide Ticagrelor Tranexamic Acid